Uric Acid, Signs, Causes, Symptoms and Treatment

UNDERSTANDING DISEASES OF URIC ACID

  

Uric Acid - Disease of gout or gout is a condition that can cause the symptoms of pain are not bearable, swelling, and a sense of heat in the joints. Although all joints in the body can be affected by gout, most often stricken with finger joints is knees, ankles, and toes. Lay people sometimes refer to these diseases as gout.

Men are more prone to the disease affected uric acid as compared to women, particularly when their age over 30 years. In women, the disease is usually risky breadnut after menopause.

People affected by the attack of the disease gout will typically feel symptoms of rapid development in the first few hours. The pain can last for 3-10 days. The swelling is not only happening in the joints, but also in the area around the joints accompanied by a flushed skin color. At this stage, the sufferer may not able to move freely.

 people often mistakenly equate the diseases of uric acid (gout/piraí) with rheumatism. Even though arthritis is a general term used to describe pain in the joints or muscles that are experiencing inflammation. Diseases of uric acid (gout/piraí) are only one of the causes of pain in the joints. Recognize symptoms and signs of gout can help a person distinguish with joint pain caused by other conditions.

A lot of people thought when the levels of uric acid in the blood (hyperuricemia), it will be affected by gout. This is not true, because only about 1/3 hyperuricemia sufferers are having gout.

Disease-causing uric acid

The symptoms of pain and swelling in diseases of uric acid caused by the piercing sharp crystals around joints that are formed by the buildup of uric acid substances. Someone who likes to eat foods that cause an increase in uric acid (e.g. organ meats, seafood, red meat) and someone who is fond of consuming alcoholic beverages will be exposed to high-risk disease gout. In addition, the disease is also prone to be experienced by those who suffer from obesity, diabetes, hypertension, or chronic kidney disease.

According to the study, a person who has a family of uric acid disease sufferers may also be exposed to the same conditions. In other words, the disease is genetic in nature as well.

The diagnosis of diseases of uric acid

appear to a doctor if you feel any symptoms of the disease gout. In doing the diagnosis, the doctor will perform an examination or a test to ensure there are sodium uric crystals in joints. This needs to be done because there are other types of diseases that can cause symptoms resembling disease gout. Examination of the levels of uric acid in the blood is also usually done.

Before doing the test, usually the doctor will first ask about:

• the location of painful joints.
• How often you experience symptoms and how quickly such symptoms appear.
• certain drugs that you are consuming.
• History of uric acid disease in your family.

Handling of uric acid disease

Handling of a uric acid disease has two main objectives, namely to alleviate symptoms and prevent attacks happen again.

To relieve the symptoms of the disease gout, you can attach the ice on the painful joints. You can also consume drugs pain reliever, such as colchicine, OAINS (nonsteroid anti-inflammatory drugs), and the drugs are steroids.

Whereas in order to prevent a recurrence of the disease attacks gout, you can consume the drug-lowering uric acid levels (such as allopurinol). In addition, you are required to abstain from food-food triggers gout disease and lose weight. Preferred foods low in calories to support the efforts of getting the ideal body weight.

The combination of drugs from a doctor, as well as a generally healthy lifestyle behavior, proved to be potent in lowering the levels of uric acid and dissolve crystals sharp has formed. With that combination, then the expected disease gout patients no longer experience a relapse.

Complications of gout disease

Although the disease is rare complications of uric acid, still we should beware. Some possible complications, including:

• the emergence of hard lumps (tofu) around an area that is experiencing inflammation.
• Permanent Joint Damage due to inflammation that continues to take place and in the joint tofi damaging cartilage and bones of the joint itself. Permanent damage usually happens in the case of diseases of uric acid that was neglected for many years.
•  kidney stones caused by deposition of uric acid that mixed with calcium in the kidneys.

SYMPTOMS OF GOUT DISEASE

  

Joints that suddenly felt very sick (especially the big toe joint), is illness symptoms common gout. Often sufferers of the disease are the difficulty to walk due to the pain which is very annoying. Even though it can appear at any time, but generally more symptoms usually felt in the evening.

Not only the big toe joints, other joints located on the ends of the limbs are also vulnerable to attack disease gout. An example is an ankle joint, the soles of the feet, knees, wrists, fingers, and elbows.

The pain usually develops quickly within the next few hours. This will be great pain accompanied by swelling, heat sensation, as well as the appearance of redness on the skin that lines the joint.

The disease attacks gout generally take place in the next 3-10 day. When symptoms subside and swelling deflate, the skin around the joints which would appear scaly, flaky, and itch. Although the attack could subside by itself, this condition should not be ignored. The treatment must still be done, inter alia to prevent the risk of recurrence with the severity of the symptoms increased, the risk of spread to other joints, and the risk of permanent damage to the joint.

DISEASE-CAUSING URIC ACID

  

A buildup of uric acid in the joints is the cause of disease of gout. In fact, uric acid is formed from the decomposition of waste substances purines inside the body's cells. Most uric acid is thrown through the kidneys in the form of urine and some other small discarded through the digestive tract in the form of feces.

If uric acid is expelled from the body is much less than the amount produced, then the uric acid would accumulate and form sharp crystals of sodium micro-sized veins converge in the joints or around a joint network. When the sharp crystals into joints and annoying software layer joints, then there was inflammation that feels very sick.

There are several factors that could trigger a rise in the levels of uric acid in the blood, one of which is the food material into portions high that we consume. Examples of these foods are animal offal (heart, liver, kidney), seafood (shellfish, crabs, anchovies, mackerel), and red meat (beef, goat, Buffalo).

In addition to the food, we could also be risky experience uric same buildup in the blood if sweet drinks consumed (either natural or artificial sugar) and alcohol in excess.

The risk of developing diseases of uric acid are also high for people who are undergoing treatment use certain types of drugs, such as aspirin, the drug niacin, an inhibitor of angiotensin converter enzyme (ACE inhibitors) drug, an inhibitor of beta (beta blockers ), cyclosporine, diuretics, chemotherapy, and drugs.

Whereas if viewed as a form of uric acid disease complications, high risk experienced by those who are suffering from chronic kidney disease, diabetes, hypertension, high cholesterol, obesity, osteoarthritis, psoriasis, and the metabolic syndrome.

Apart from the four factors above, disease triggers gout also allegedly got into a group alias derivative disease genetic diseases. This means that those who have a family member afflicted gout risk experiencing the same condition. According to the study, the proportion of this risk was 20 percent.

More at least the number of women affected by the disease of gout than men likely linked to menopause conditions. After menopause, women experience uric acid levels can increase and start to feel symptoms of disease gout.

Regardless of the above factors, there are also some people who have high levels of uric acid in their blood, but not found the formation of uric crystals of sodium in her joints. In addition, among some people who have the same levels of uric acid, however, the level of their vulnerability will vary. About it, until now there has been no definite explanation.

THE DIAGNOSIS OF DISEASES OF URIC ACID

  

Meet the doctor if you feel any symptoms of the disease gout though often subside on its own. Medical handling required to prevent recurrence and worsening of the condition over time.

To truly ascertain whether you suffer from gout disease, doctors need to do special tests to measure levels of uric acid or see the existence of the substance crystals in the joints. But before doing the test, first the doctor usually will ask you about a few things, namely:

• the location of painful joints.
• how fast developing symptoms and how often the symptoms appear.
• foods with high levels of purine may often you consume.
• an aperitif or drink high fructose sweets that may often you consume.
• drugs trigger diseases of uric acid that maybe you are using.
• diseases with complications of diseases of uric acid that maybe you are suffering.
• Your family health history.

The answer to the above questions will be used to support doctors test results done.

One of the types of tests that can detect the presence of uric acid crystals is a test of the joint fluid. In these tests, the doctor will take a sample of synovial fluid in the joints that are experiencing inflammation using a needle and inspect it through a microscope. If the patient is indeed suffering from gout disease, usually sodium uric crystals are almost always seen in a sample of liquid synovial. This method also helps the doctor to make sure that the symptoms are not caused by other diseases (such as septic arthritis with swelling symptoms and the appearance of pain is not unbearable accompanied by fever).

The second type of test that is scanning ultrasound (ultrasound). This test is used Center and now because it is considered the most simple and safe way to detect the presence of uric crystals of sodium in the joints that are experiencing inflammation or inside the layers of the skin.

In addition, the doctor may also need to do a blood test to measure levels of uric acid in the blood. The test is also usually performed on a half moon or one month after the occurrence of an attack of symptoms. The reason doctors need to wait during the time it is because of the level of uric acid tends to fall when the attack took place.

X-ray inspection method is typically only used by physicians for the purpose of the waiver. Because even though it is less able to detect the presence of uric acid crystals in the joints, this inspection method is still capable of detecting other conditions with similar symptoms (e.g. is chondrocalcinosis or joint inflammation due to the formation of crystals calcium). When other conditions are also not found with regard to the existing joint damage, then the doctor could assume that patients suffering from the disease of gout.

Treatment Of Gout

It is important to rest with enough for you experience uric acid disease attack. Lift up Your leg and avoid joints that are experiencing inflammation from the clash. Compresses an unused joint with a bag of ice for about twenty minutes can also help relieve the pain. Do not over the time compresses an unused and don't attach the ice directly to the skin as it can damage the skin.

Immediately take medication prescribed by a doctor as soon as you feel the disease gout attacks. A common medication used to relieve inflammation and pain are a group of drugs a bitter taste nonsteroid (OAINS), such as indomethacin, naproxen, and diclofenac is, etoricoxib.

Use of OAINS side effects includes stomach ulcers and indigestion. To minimize the incidence of these side effects, the doctor will usually prescribe a proton pump inhibitor drugs (PPI) as a companion.

It is important to follow the entire usage instructions given by doctors in taking RAINS. This drug usually must be continued to be used during the attack of diseases of uric acid has not died down, until two days after the attack died down to prevent relapse.

When OAINS less able to relieve symptoms of the disease of gout or you are not allowed to consume this drug due to certain conditions, the doctor can prescribe a colchicine as a substitute that is also efficacious for relieving pain and the swelling. Colchicine rarely causes any side effects. Side effects in the form of abdominal pain, nausea, and diarrhea usually arises when these drugs are consumed in high doses.

In the case of diseases of uric acid with severe symptoms who cannot be appeased with OAINS or colchicine, a doctor will usually prescribe a corticosteroid. In addition to the drug in tablet form, it can also be given in the form of a doctor's syringe to relieve pain quickly.

When used in low doses and in a short period of time, corticosteroids rarely cause any side effects. Conversely, if used in high doses and prolonged period of this risky drugs, cause side effects, such as muscle weakness, skin feels too easy bruising, thinning of the bones, and weight gain.

Prevent the recurrence of attacks of gout disease

Foods that contain a lot of pain may increase levels of uric acid in the body and make us vulnerable to developing symptoms of the disease gout. 

Therefore, to avoid such food. Examples of foods that contain a lot of pain were offal (heart, liver, kidney, and brain), seafood (shellfish, crabs, and shrimp), red meats, foods containing yeast, and contains many fish oil (sardine, mackerel, and anchovy). In addition, because the offal, the levels of uric acid may also increase if we eating too many sweet treats, sweet drinks, and alcoholic beverages. Types of alcoholic drinks that are most at risk of triggering attacks disease gout are beer, whiskey, and vodka.

Reduce your weight if you have body proportions of overweight (obesity) because the physical as it will make You vulnerable to attack disease gout. In addition, do not override the importance of exercise is enough so that your body is always healthy and fit. If by chance you are currently feeling the symptoms of diseases of uric acid, but want to maintain physical fitness, avoid doing a sport that can put pressure on your joints are inflamed. We recommend that you select a sports swimming because the water can sustain the weight so that the joints are not too experienced the pressure.

Drinking plain water to taste each day. Besides can prevent yourself from dehydration, water can also streamline the disposal of uric acid via the urine so that the risk of formation of crystals becomes minimal. It is recommended that we drink around 6-8 glass of mineral water per day, even more, if we routinely do sports or are on the bottom of the hot weather.

In addition to the settings through food, drink, weight loss, and exercise, disease symptoms gout attacks can also be prevented through drugs prescribed by the doctor. Preventive medicine gout usually reserved for patients who often have relapse or patients who have been exposed to the complications of the disease gout. The following types of preventive medicine disease gout attacks.

 Allopurinol. A Tablet taken once a day may help the body lowers the amount of uric acid by way of inhibiting the enzymes that convert the purine into uric acid. Allopurinol dosage should be adjusted to ensure the achievement of uric acid levels is appropriate targets, i.e. under 360 umol/L or 6 mg/dl. 

The dose of these drugs will usually increase each week, depending on the 3-4 to the results of examination of blood. Crystals of uric acid in the body will generally disappear completely within the next 1-2 years during treatment. Sometimes the attacks of gout can occur when you first use the treatment with allopurinol. 

This is caused by the shrinking of crystals that are in the cartilage of the joints due to uric acid levels are drastically reduced to below the point of saturation. The shrinking of the Crystal becomes easier to escape from the cartilage into the joint cavity and ended up making the lining of the joints or synovium experience inflammation. But don't worry this will stop once your body is completely clean of uric crystals of sodium. 

The most important is You don't give up undergoing therapy this treatment for the sake of maximum results. Side effects that may arise from the use of allopurinol are a headache, indigestion, diarrhea, and skin rashes. Side effects specific to skin rashes, meet a doctor if you experience it because it could be a sign of an allergy to the drug.

 Probenecid. The drug is able to lower the levels of uric acid by way of improving the ability of the kidneys to get rid of it. Side effects that may be there after using probenecid are abdominal pain, skin rash, and disease risk of kidney stones.

Prevent uric acid with vitamin C

According to a study, vitamin C is capable of preventing the diseases of uric acid by means of improving the performance of the kidneys in the dispose of uric acid that exists in our body. The recommended dose of vitamin C was 500 milligrams per day.

But before You taking supplements of vitamin C, you should consult the doctor in advance lest You have health issues that could grow worse or is undergoing treatment with a drug that should not be used along with supplements of vitamin c.

COMPLICATIONS OF GOUT DISEASE

  

There are a few other health problems that could arise due to disease of gout, especially when the condition is ignored or left untreated. Some examples of complications due to uric acid which are diseases of the Kidney stone, the appearance of a lump-lump under the skin called tofu, and damage to the joints, and psychological problems.

Kidney stone disease

Uric acid in the body is issued in the form of urine through kidneys. Sometimes these create uric acid deposits-deposits in the kidneys, especially if simply applied. If the size of the sediment is still small, the body will get rid of it naturally through the urinary tract. However, if the size is too large, then it can cause diseases of the kidney stones.

In addition to sensations such as always want to urinate, usually, a kidney stone disease sufferers will feel pain during urination due to disruption of the flow of urine. If not immediately treated, the disease could cause an infection in the urinary system. According to the data, approximately 10-25 percent of the sufferers of the disease gout participated and experienced the problem of kidney stones. Doctors will usually provide a medication that can dissolve kidney stones and be lowering the levels of acidity in the urine. In addition, the Kidney stone sufferers are also advised to drink plenty of water to remove sediment-deposition of uric acid.

The emergence of the bump-bump tofi

Tofi is the vapor of the small white or yellow underneath the skin formed from the accumulation of uric acid crystals. Tofi bumps usually appear on the knees, elbows, toes and fingers, forearm, heel, or even the ears.

Tofi usually appear in severe gout sufferers or long untreated. But there is also an emerging tofi in people who have not even ever experience uric acid disease attack. Although it often does not cause pain, daily routines (such as dressing or eating) could be interrupted if tofi is growing on the fingers.

The emergence of tofi became signals that the treatment of diseases of uric acid can not too late again and should be immediately done. If the levels of uric acid successfully lowered, tofi will gradually shrink over soluble uric crystals of sodium. But conversely, if left unchecked, then continue tofi will enlarge and eventually cause pain.

The inflamed Tofi could even break apart and be removing the liquid resembles toothpaste that consists of a mixture of pus and uric crystals. Immediately consult the doctor if your body is covered with large tofi or hurt. If deemed necessary, the doctor will perform the surgery to remove the tofi.

Damage to the joints

Uric crystals of sodium that continue to pile up and form tofi in joints can gradually damage the joints. It's not impossible if the damage to the joints permanently can happen in these conditions failed to handle. If the joint is damaged, so the operation must be performed by a doctor forced to repair or replace it.

Psychological problems

Mood swings and stress could have been experienced by sufferers of the disease gout. Not only because of the extraordinary pain to be felt, but also the effects of this condition that makes daily routine becomes disturbed. If omitted, then it is not impossible that can lead to depression. Thus, before more serious psychological problems, soon encountered the doctor if you are a sufferer of uric acid and sickness You feel stressed to the conditions experienced.